UV-Vis spectrophotometry has a diverse range of applications in both academia and industry. Here are some articles detailing common - and novel - applications.
1. Characterisation and effect of pharmaceuticals
In early drug discovery and development, UV-Vis is a common technique implemented to identify and produce the active pharmaceutical ingredient in medicines. It is also implemented to quantify the level of impurities present. For oral medicines, the analysis of the rate and extent of drug release or dissolution can be measured using spectrophotometry techniques.
a. Ultraviolet-Visible Spectrophotometry in Pharmaceutical Analysis
b. Determination of celecoxib in pharmaceutical formulations using UV spectrophotometry and liquid chromatography
2. Characterisation and uses of nanoparticles
Nanoparticles are utilised in a vast number of science and industrial applications, from cosmetics and paints to medicines and construction materials. In order to use these materials correctly and safely, we must determine with confidence the size and chemical make-up of these nanoparticles. This can be done with UV-Vis spectrophotometry.
a. Determination of Size and Concentration of Gold Nanoparticles from UV−Vis Spectra
b. Size Distribution of Silver Nanoparticles: UV-Visible Spectroscopic Assessment
c. Green synthesis of zinc oxide nanoparticles: a comparison
3. Quality analysis of water and determination of impurities
The availability of drinkable water is of upmost importance to life on earth. Impurities such as heavy metals or some microbiological contaminants can have disastrous effects on local human and wildlife populations. It is therefore useful to be able to asses the quality of water to determine how to purify it, and then to reliably confirm the level of purity. This can be done using UV-Vis methods.
a. Advances on Water Quality Detection by UV-Vis Spectroscopy
b. Characterization of dissolved organic matter in cave and spring waters using UV–Vis absorbance and fluorescence spectroscopy